- Blood Matters: From Inherited Illness to Designer Babies, How the World and I Found Ourselves in the Future of the Gene by Masha Gessen
- The Drunkard's Walk: How Randomness Rules Our Lives by Leonard Mlodinow
- Predictably Irrational: The Hidden Forces That Shape Our Decisions by Dan Ariely
- The Superorganism: The Beauty, Elegance, and Strangeness of Insect Societies by Bert Hölldobler and Edward O. Wilson.
- Traffic: Why We Drive the Way We Do (And What It Says About Us) by Tom Vanderbilt
Thomas L. Friedman's Hot, Flat and Crowded: Why We Need a Green Revolution — and How It Can Renew America is a related book that I think a lot of people will be selecting this year.